P10747 (P10747)

Overview
Predicted structure (AF):
AF-P10747-F1-model_v4
Uniprot entry:
P10747
Gene:
P10747
Protein length:
220 residues
Mutations found:
4179
Benign based on D2Deep prediction:
2503 out of 4179 mutations
Pathogenic based on D2Deep prediction:
1676 out of 4179 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4179 mutations across 220 unique positions. There are 2503 benign and 1676 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 N 19 0 19 0.026 0.618 View mutations
102 L 16 3 19 0.214 0.496 View mutations
103 Y 11 8 19 0.429 0.451 View mutations
104 V 4 15 19 0.747 0.462 View mutations
105 N 1 18 19 0.879 0.611 View mutations
106 Q 8 11 19 0.576 0.541 View mutations
107 T 16 3 19 0.212 0.348 View mutations
108 D 5 14 19 0.611 0.677 View mutations
109 I 16 3 19 0.177 0.233 View mutations
110 Y 2 17 19 0.871 0.824 View mutations
111 F 5 14 19 0.753 0.677 View mutations
112 C 0 19 19 0.961 0.928 View mutations
113 K 16 3 19 0.214 0.303 View mutations
114 I 11 8 19 0.450 0.440 View mutations
115 E 18 1 19 0.113 0.220 View mutations
116 V 18 1 19 0.135 0.314 View mutations
117 M 6 13 19 0.602 0.618 View mutations
118 Y 12 7 19 0.360 0.427 View mutations
119 P 2 17 19 0.810 0.804 View mutations
120 P 0 19 19 0.980 0.895 View mutations
121 P 0 19 19 1.000 0.847 View mutations
122 Y 1 18 19 0.919 0.717 View mutations
123 L 2 17 19 0.870 0.629 View mutations
124 D 9 10 19 0.538 0.505 View mutations
125 N 1 18 19 0.927 0.627 View mutations