P11309 (P11309)

Overview
Predicted structure (AF):
AF-P11309-F1-model_v4
Uniprot entry:
P11309
Gene:
P11309
Protein length:
313 residues
Mutations found:
5946
Benign based on D2Deep prediction:
3712 out of 5946 mutations
Pathogenic based on D2Deep prediction:
2234 out of 5946 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5946 mutations across 313 unique positions. There are 3712 benign and 2234 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 D 15 4 19 0.244 0.386 View mutations
177 L 14 5 19 0.254 0.484 View mutations
178 N 19 0 19 0.001 0.465 View mutations
179 R 19 0 19 0.016 0.382 View mutations
180 G 16 3 19 0.165 0.494 View mutations
181 E 18 1 19 0.072 0.432 View mutations
182 L 10 9 19 0.459 0.498 View mutations
183 K 10 9 19 0.526 0.490 View mutations
184 L 2 17 19 0.869 0.687 View mutations
185 I 11 8 19 0.484 0.454 View mutations
186 D 19 0 19 0.000 0.190 View mutations
187 F 0 19 19 1.000 0.903 View mutations
188 G 1 18 19 0.927 0.815 View mutations
189 S 1 18 19 0.942 0.683 View mutations
190 G 1 18 19 0.897 0.703 View mutations
191 A 2 17 19 0.909 0.609 View mutations
192 L 14 5 19 0.256 0.498 View mutations
193 L 8 11 19 0.620 0.522 View mutations
194 K 12 7 19 0.420 0.419 View mutations
195 D 6 13 19 0.680 0.529 View mutations
196 T 19 0 19 0.002 0.370 View mutations
197 V 19 0 19 0.002 0.364 View mutations
198 Y 1 18 19 0.904 0.640 View mutations
199 T 19 0 19 0.009 0.414 View mutations
200 D 2 17 19 0.869 0.536 View mutations