P11309 (P11309)

Overview
Predicted structure (AF):
AF-P11309-F1-model_v4
Uniprot entry:
P11309
Gene:
P11309
Protein length:
313 residues
Mutations found:
5946
Benign based on D2Deep prediction:
3712 out of 5946 mutations
Pathogenic based on D2Deep prediction:
2234 out of 5946 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5946 mutations across 313 unique positions. There are 3712 benign and 2234 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 V 14 5 19 0.271 0.407 View mutations
127 Q 2 17 19 0.896 0.505 View mutations
128 D 0 19 19 1.000 0.649 View mutations
129 L 10 9 19 0.488 0.489 View mutations
130 F 0 19 19 0.997 0.591 View mutations
131 D 0 19 19 1.000 0.641 View mutations
132 F 2 17 19 0.899 0.575 View mutations
133 I 2 17 19 0.899 0.665 View mutations
134 T 5 14 19 0.654 0.563 View mutations
135 E 18 1 19 0.064 0.415 View mutations
136 R 9 10 19 0.515 0.436 View mutations
137 G 2 17 19 0.893 0.601 View mutations
138 A 13 6 19 0.297 0.429 View mutations
139 L 3 16 19 0.849 0.616 View mutations
140 Q 19 0 19 0.016 0.483 View mutations
141 E 17 2 19 0.191 0.401 View mutations
142 E 19 0 19 0.000 0.620 View mutations
143 L 19 0 19 0.001 0.546 View mutations
144 A 6 13 19 0.694 0.520 View mutations
145 R 19 0 19 0.002 0.462 View mutations
146 S 19 0 19 0.007 0.518 View mutations
147 F 4 15 19 0.777 0.527 View mutations
148 F 19 0 19 0.000 0.406 View mutations
149 W 19 0 19 0.000 0.541 View mutations
150 Q 19 0 19 0.000 0.414 View mutations