P11309 (P11309)

Overview
Predicted structure (AF):
AF-P11309-F1-model_v4
Uniprot entry:
P11309
Gene:
P11309
Protein length:
313 residues
Mutations found:
5946
Benign based on D2Deep prediction:
3712 out of 5946 mutations
Pathogenic based on D2Deep prediction:
2234 out of 5946 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5946 mutations across 313 unique positions. There are 3712 benign and 2234 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 V 9 10 19 0.568 0.506 View mutations
152 L 0 19 19 0.971 0.540 View mutations
153 E 19 0 19 0.037 0.450 View mutations
154 A 19 0 19 0.007 0.456 View mutations
155 V 1 18 19 0.935 0.582 View mutations
156 R 9 10 19 0.453 0.440 View mutations
157 H 17 2 19 0.109 0.483 View mutations
158 C 0 19 19 0.988 0.549 View mutations
159 H 17 2 19 0.160 0.414 View mutations
160 N 19 0 19 0.009 0.480 View mutations
161 C 15 4 19 0.214 0.496 View mutations
162 G 0 19 19 0.996 0.748 View mutations
163 V 1 18 19 0.938 0.743 View mutations
164 L 3 16 19 0.838 0.656 View mutations
165 H 0 19 19 0.994 0.791 View mutations
166 R 0 19 19 1.000 0.839 View mutations
167 D 19 0 19 0.006 0.181 View mutations
168 I 2 17 19 0.915 0.747 View mutations
169 K 12 7 19 0.348 0.406 View mutations
170 D 2 17 19 0.904 0.631 View mutations
171 E 0 19 19 0.999 0.684 View mutations
172 N 10 9 19 0.483 0.484 View mutations
173 I 19 0 19 0.028 0.279 View mutations
174 L 17 2 19 0.116 0.339 View mutations
175 I 6 13 19 0.678 0.533 View mutations