P11487 (P11487)

Overview
Predicted structure (AF):
AF-P11487-F1-model_v4
Uniprot entry:
P11487
Gene:
P11487
Protein length:
239 residues
Mutations found:
4540
Benign based on D2Deep prediction:
1978 out of 4540 mutations
Pathogenic based on D2Deep prediction:
2562 out of 4540 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4540 mutations across 239 unique positions. There are 1978 benign and 2562 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 K 19 0 19 0.009 0.472 View mutations
102 R 10 9 19 0.444 0.491 View mutations
103 G 2 17 19 0.844 0.773 View mutations
104 R 0 19 19 1.000 0.739 View mutations
105 L 0 19 19 1.000 0.830 View mutations
106 Y 0 19 19 0.987 0.694 View mutations
107 A 3 16 19 0.829 0.651 View mutations
108 S 0 19 19 0.988 0.687 View mutations
109 E 14 5 19 0.221 0.449 View mutations
110 H 17 2 19 0.111 0.394 View mutations
111 Y 1 18 19 0.924 0.585 View mutations
112 S 8 11 19 0.581 0.510 View mutations
113 A 17 2 19 0.113 0.489 View mutations
114 E 15 4 19 0.230 0.356 View mutations
115 C 0 19 19 0.999 0.767 View mutations
116 E 7 12 19 0.613 0.560 View mutations
117 F 0 19 19 1.000 0.806 View mutations
118 V 3 16 19 0.792 0.691 View mutations
119 E 0 19 19 1.000 0.937 View mutations
120 R 2 17 19 0.900 0.822 View mutations
121 I 0 19 19 0.978 0.908 View mutations
122 H 0 19 19 0.999 0.854 View mutations
123 E 0 19 19 1.000 0.923 View mutations
124 L 0 19 19 1.000 0.962 View mutations
125 G 0 19 19 1.000 0.937 View mutations