P11802 (CDK4)

Overview
Predicted structure (AF):
AF-P11802-F1-model_v4
Uniprot entry:
P11802
Gene:
CDK4
Protein length:
303 residues
Mutations found:
5756
Benign based on D2Deep prediction:
3605 out of 5756 mutations
Pathogenic based on D2Deep prediction:
2151 out of 5756 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5756 mutations across 303 unique positions. There are 3605 benign and 2151 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 G 19 0 19 0.028 0.594 View mutations
152 G 8 11 19 0.589 0.517 View mutations
153 T 19 0 19 0.010 0.424 View mutations
154 V 18 1 19 0.065 0.329 View mutations
155 K 0 19 19 1.000 0.810 View mutations
156 L 17 2 19 0.144 0.318 View mutations
157 A 2 17 19 0.873 0.828 View mutations
158 D 5 14 19 0.649 0.695 View mutations
159 F 2 17 19 0.852 0.793 View mutations
160 G 10 9 19 0.521 0.478 View mutations
161 L 0 19 19 0.997 0.802 View mutations
162 A 0 19 19 1.000 0.783 View mutations
163 R 1 18 19 0.945 0.630 View mutations
164 I 3 16 19 0.814 0.581 View mutations
165 Y 8 11 19 0.512 0.521 View mutations
166 S 18 1 19 0.183 0.406 View mutations
167 Y 19 0 19 0.005 0.463 View mutations
168 Q 19 0 19 0.060 0.386 View mutations
169 M 19 0 19 0.002 0.331 View mutations
170 A 19 0 19 0.005 0.396 View mutations
171 L 2 17 19 0.896 0.660 View mutations
172 T 16 3 19 0.235 0.345 View mutations
173 P 19 0 19 0.023 0.419 View mutations
174 V 18 1 19 0.097 0.390 View mutations
175 V 4 15 19 0.812 0.641 View mutations