P15976 (GATA1)

Overview
Predicted structure (AF):
AF-P15976-F1-model_v4
Uniprot entry:
P15976
Gene:
GATA1
Protein length:
413 residues
Mutations found:
7846
Benign based on D2Deep prediction:
3634 out of 7846 mutations
Pathogenic based on D2Deep prediction:
4212 out of 7846 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7846 mutations across 413 unique positions. There are 3634 benign and 4212 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 T 19 0 19 0.002 0.510 View mutations
102 G 19 0 19 0.007 0.458 View mutations
103 L 7 12 19 0.624 0.443 View mutations
104 Y 13 6 19 0.381 0.446 View mutations
105 P 1 18 19 0.921 0.419 View mutations
106 A 13 6 19 0.361 0.499 View mutations
107 S 18 1 19 0.095 0.477 View mutations
108 T 18 1 19 0.093 0.554 View mutations
109 V 19 0 19 0.010 0.417 View mutations
110 C 19 0 19 0.022 0.611 View mutations
111 P 19 0 19 0.015 0.495 View mutations
112 T 19 0 19 0.012 0.690 View mutations
113 R 19 0 19 0.004 0.708 View mutations
114 E 19 0 19 0.010 0.559 View mutations
115 D 19 0 19 0.036 0.621 View mutations
116 S 17 2 19 0.128 0.630 View mutations
117 P 15 4 19 0.281 0.567 View mutations
118 P 17 2 19 0.150 0.607 View mutations
119 Q 9 10 19 0.468 0.449 View mutations
120 A 17 2 19 0.121 0.561 View mutations
121 V 17 2 19 0.148 0.637 View mutations
122 E 15 4 19 0.201 0.516 View mutations
123 D 12 7 19 0.375 0.471 View mutations
124 L 8 11 19 0.531 0.428 View mutations
125 D 8 11 19 0.622 0.431 View mutations