P16403 (H1-2)

Overview
Predicted structure (AF):
AF-P16403-F1-model_v4
Uniprot entry:
P16403
Gene:
H1-2
Protein length:
213 residues
Mutations found:
4046
Benign based on D2Deep prediction:
2539 out of 4046 mutations
Pathogenic based on D2Deep prediction:
1507 out of 4046 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4046 mutations across 213 unique positions. There are 2539 benign and 1507 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 A 19 0 19 0.000 0.000 View mutations
102 S 3 16 19 0.878 0.800 View mutations
103 G 0 19 19 1.000 0.973 View mutations
104 S 0 19 19 1.000 0.922 View mutations
105 F 0 19 19 1.000 0.871 View mutations
106 K 1 18 19 0.950 0.658 View mutations
107 L 8 11 19 0.525 0.530 View mutations
108 N 6 13 19 0.642 0.503 View mutations
109 K 16 3 19 0.193 0.394 View mutations
110 K 19 0 19 0.003 0.514 View mutations
111 A 18 1 19 0.034 0.564 View mutations
112 A 18 1 19 0.065 0.595 View mutations
113 S 19 0 19 0.000 0.681 View mutations
114 G 19 0 19 0.011 0.732 View mutations
115 E 16 3 19 0.186 0.636 View mutations
116 A 19 0 19 0.018 0.781 View mutations
117 K 7 12 19 0.596 0.398 View mutations
118 P 19 0 19 0.007 0.760 View mutations
119 K 19 0 19 0.014 0.818 View mutations
120 V 18 1 19 0.077 0.836 View mutations
121 K 18 1 19 0.142 0.810 View mutations
122 K 19 0 19 0.002 0.832 View mutations
123 A 18 1 19 0.149 0.843 View mutations
124 G 18 1 19 0.138 0.823 View mutations
125 G 9 10 19 0.484 0.460 View mutations