P16422 (EPCAM)

Overview
Predicted structure (AF):
AF-P16422-F1-model_v4
Uniprot entry:
P16422
Gene:
EPCAM
Protein length:
314 residues
Mutations found:
5965
Benign based on D2Deep prediction:
3951 out of 5965 mutations
Pathogenic based on D2Deep prediction:
2014 out of 5965 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5965 mutations across 314 unique positions. There are 3951 benign and 2014 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 E 19 0 19 0.003 0.484 View mutations
102 S 17 2 19 0.137 0.592 View mutations
103 G 0 19 19 0.985 0.752 View mutations
104 L 6 13 19 0.693 0.452 View mutations
105 F 0 19 19 0.998 0.781 View mutations
106 K 7 12 19 0.606 0.546 View mutations
107 A 18 1 19 0.048 0.225 View mutations
108 K 9 10 19 0.477 0.512 View mutations
109 Q 18 1 19 0.061 0.204 View mutations
110 C 0 19 19 0.999 0.814 View mutations
111 N 2 17 19 0.801 0.612 View mutations
112 G 17 2 19 0.142 0.415 View mutations
113 T 16 3 19 0.272 0.438 View mutations
114 S 18 1 19 0.052 0.485 View mutations
115 M 18 1 19 0.096 0.432 View mutations
116 C 8 11 19 0.489 0.553 View mutations
117 W 0 19 19 0.996 0.824 View mutations
118 C 0 19 19 0.950 0.883 View mutations
119 V 1 18 19 0.922 0.946 View mutations
120 N 3 16 19 0.856 0.807 View mutations
121 T 2 17 19 0.899 0.753 View mutations
122 A 7 12 19 0.615 0.604 View mutations
123 G 0 19 19 1.000 1.000 View mutations
124 V 1 18 19 0.938 0.864 View mutations
125 R 0 19 19 1.000 0.901 View mutations