P21912 (SDHB)

Overview
Predicted structure (AF):
AF-P21912-F1-model_v4
Uniprot entry:
P21912
Gene:
SDHB
Protein length:
280 residues
Mutations found:
5319
Benign based on D2Deep prediction:
3093 out of 5319 mutations
Pathogenic based on D2Deep prediction:
2226 out of 5319 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5319 mutations across 280 unique positions. There are 3093 benign and 2226 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 C 19 0 19 0.000 0.244 View mutations
102 A 3 16 19 0.847 0.616 View mutations
103 M 2 17 19 0.848 0.604 View mutations
104 N 3 16 19 0.845 0.546 View mutations
105 I 0 19 19 1.000 0.504 View mutations
106 N 12 7 19 0.362 0.446 View mutations
107 G 15 4 19 0.226 0.465 View mutations
108 G 14 5 19 0.377 0.479 View mutations
109 N 8 11 19 0.536 0.507 View mutations
110 T 19 0 19 0.009 0.473 View mutations
111 L 5 14 19 0.735 0.521 View mutations
112 A 6 13 19 0.719 0.440 View mutations
113 C 15 4 19 0.180 0.426 View mutations
114 T 16 3 19 0.132 0.565 View mutations
115 R 17 2 19 0.163 0.656 View mutations
116 R 19 0 19 0.017 0.703 View mutations
117 I 9 10 19 0.497 0.448 View mutations
118 D 19 0 19 0.004 0.746 View mutations
119 T 19 0 19 0.006 0.763 View mutations
120 N 19 0 19 0.018 0.819 View mutations
121 L 19 0 19 0.002 0.816 View mutations
122 N 19 0 19 0.013 0.784 View mutations
123 K 19 0 19 0.041 0.765 View mutations
124 V 19 0 19 0.004 0.869 View mutations
125 S 15 4 19 0.235 0.581 View mutations