P21912 (SDHB)

Overview
Predicted structure (AF):
AF-P21912-F1-model_v4
Uniprot entry:
P21912
Gene:
SDHB
Protein length:
280 residues
Mutations found:
5319
Benign based on D2Deep prediction:
3093 out of 5319 mutations
Pathogenic based on D2Deep prediction:
2226 out of 5319 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5319 mutations across 280 unique positions. There are 3093 benign and 2226 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 K 7 12 19 0.537 0.404 View mutations
127 I 1 18 19 0.940 0.538 View mutations
128 Y 0 19 19 0.993 0.445 View mutations
129 P 3 16 19 0.823 0.582 View mutations
130 L 0 19 19 0.999 0.689 View mutations
131 P 0 19 19 1.000 0.651 View mutations
132 H 0 19 19 0.995 0.588 View mutations
133 M 1 18 19 0.922 0.452 View mutations
134 Y 4 15 19 0.765 0.441 View mutations
135 V 7 12 19 0.592 0.525 View mutations
136 I 3 16 19 0.850 0.523 View mutations
137 K 4 15 19 0.775 0.574 View mutations
138 D 0 19 19 1.000 0.654 View mutations
139 L 2 17 19 0.916 0.671 View mutations
140 V 1 18 19 0.936 0.583 View mutations
141 P 6 13 19 0.654 0.502 View mutations
142 D 9 10 19 0.423 0.434 View mutations
143 L 19 0 19 0.000 0.415 View mutations
144 S 11 8 19 0.382 0.442 View mutations
145 N 19 0 19 0.031 0.613 View mutations
146 F 16 3 19 0.143 0.424 View mutations
147 Y 15 4 19 0.237 0.461 View mutations
148 A 19 0 19 0.002 0.549 View mutations
149 Q 13 6 19 0.300 0.413 View mutations
150 Y 19 0 19 0.004 0.425 View mutations