P21912 (SDHB)

Overview
Predicted structure (AF):
AF-P21912-F1-model_v4
Uniprot entry:
P21912
Gene:
SDHB
Protein length:
280 residues
Mutations found:
5319
Benign based on D2Deep prediction:
3093 out of 5319 mutations
Pathogenic based on D2Deep prediction:
2226 out of 5319 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5319 mutations across 280 unique positions. There are 3093 benign and 2226 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 E 14 5 19 0.284 0.406 View mutations
177 R 1 18 19 0.923 0.605 View mutations
178 E 18 1 19 0.047 0.533 View mutations
179 K 19 0 19 0.019 0.436 View mutations
180 L 2 17 19 0.890 0.618 View mutations
181 D 4 15 19 0.785 0.584 View mutations
182 G 2 17 19 0.853 0.586 View mutations
183 L 4 15 19 0.750 0.553 View mutations
184 Y 2 17 19 0.913 0.603 View mutations
185 E 6 13 19 0.671 0.583 View mutations
186 C 3 16 19 0.797 0.714 View mutations
187 I 1 18 19 0.947 0.700 View mutations
188 L 1 18 19 0.947 0.730 View mutations
189 C 0 19 19 1.000 0.819 View mutations
190 A 3 16 19 0.765 0.600 View mutations
191 C 1 18 19 0.949 0.630 View mutations
192 C 0 19 19 1.000 0.748 View mutations
193 S 3 16 19 0.852 0.602 View mutations
194 T 2 17 19 0.911 0.616 View mutations
195 S 3 16 19 0.847 0.661 View mutations
196 C 2 17 19 0.902 0.759 View mutations
197 P 6 13 19 0.691 0.626 View mutations
198 S 1 18 19 0.933 0.758 View mutations
199 Y 2 17 19 0.895 0.677 View mutations
200 W 0 19 19 1.000 0.760 View mutations