P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 G 17 2 19 0.117 0.667 View mutations
227 S 19 0 19 0.002 0.683 View mutations
228 P 18 1 19 0.054 0.637 View mutations
229 L 8 11 19 0.584 0.428 View mutations
230 R 15 4 19 0.234 0.574 View mutations
231 P 19 0 19 0.024 0.753 View mutations
232 G 15 4 19 0.223 0.623 View mutations
233 L 12 7 19 0.394 0.542 View mutations
234 A 10 9 19 0.525 0.487 View mutations
235 T 18 1 19 0.082 0.758 View mutations
236 M 19 0 19 0.000 0.758 View mutations
237 G 11 8 19 0.353 0.510 View mutations
238 T 9 10 19 0.449 0.463 View mutations
239 Q 13 6 19 0.364 0.574 View mutations
240 P 19 0 19 0.011 0.719 View mutations
241 A 19 0 19 0.005 0.634 View mutations
242 T 16 3 19 0.169 0.524 View mutations
243 H 19 0 19 0.016 0.448 View mutations
244 H 19 0 19 0.000 0.440 View mutations
245 P 15 4 19 0.252 0.410 View mutations
246 I 16 3 19 0.276 0.428 View mutations
247 P 19 0 19 0.031 0.435 View mutations
248 T 3 16 19 0.840 0.447 View mutations
249 Y 0 19 19 1.000 0.440 View mutations
250 P 2 17 19 0.853 0.400 View mutations