P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 S 19 0 19 0.022 0.971 View mutations
202 A 19 0 19 0.000 0.952 View mutations
203 A 19 0 19 0.000 0.895 View mutations
204 R 19 0 19 0.018 0.703 View mutations
205 G 14 5 19 0.236 0.572 View mutations
206 E 5 14 19 0.719 0.389 View mutations
207 D 1 18 19 0.901 0.374 View mutations
208 K 11 8 19 0.530 0.455 View mutations
209 D 10 9 19 0.469 0.442 View mutations
210 G 19 0 19 0.009 0.599 View mutations
211 V 8 11 19 0.589 0.433 View mutations
212 K 0 19 19 0.999 0.402 View mutations
213 Y 2 17 19 0.914 0.405 View mutations
214 Q 2 17 19 0.836 0.346 View mutations
215 V 16 3 19 0.206 0.573 View mutations
216 S 12 7 19 0.454 0.498 View mutations
217 L 16 3 19 0.203 0.528 View mutations
218 T 10 9 19 0.438 0.459 View mutations
219 E 15 4 19 0.211 0.489 View mutations
220 S 19 0 19 0.014 0.562 View mutations
221 M 19 0 19 0.008 0.461 View mutations
222 K 18 1 19 0.157 0.456 View mutations
223 M 19 0 19 0.001 0.523 View mutations
224 E 7 12 19 0.636 0.431 View mutations
225 S 19 0 19 0.010 0.680 View mutations