P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 S 10 9 19 0.481 0.460 View mutations
252 Y 4 15 19 0.742 0.401 View mutations
253 V 10 9 19 0.459 0.469 View mutations
254 P 6 13 19 0.753 0.383 View mutations
255 A 9 10 19 0.570 0.459 View mutations
256 A 11 8 19 0.412 0.516 View mutations
257 A 6 13 19 0.643 0.379 View mutations
258 H 16 3 19 0.199 0.646 View mutations
259 D 14 5 19 0.306 0.432 View mutations
260 Y 19 0 19 0.008 0.529 View mutations
261 S 6 13 19 0.618 0.418 View mutations
262 S 2 17 19 0.899 0.366 View mutations
263 G 16 3 19 0.195 0.448 View mutations
264 L 14 5 19 0.249 0.453 View mutations
265 F 19 0 19 0.013 0.480 View mutations
266 H 19 0 19 0.088 0.500 View mutations
267 P 9 10 19 0.544 0.439 View mutations
268 G 9 10 19 0.447 0.438 View mutations
269 G 10 9 19 0.448 0.436 View mutations
270 F 4 15 19 0.821 0.420 View mutations
271 L 8 11 19 0.559 0.433 View mutations
272 G 18 1 19 0.050 0.547 View mutations
273 G 17 2 19 0.151 0.609 View mutations
274 P 11 8 19 0.356 0.513 View mutations
275 A 19 0 19 0.016 0.750 View mutations