P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 S 12 7 19 0.420 0.535 View mutations
277 S 19 0 19 0.002 0.682 View mutations
278 F 19 0 19 0.000 0.629 View mutations
279 T 15 4 19 0.234 0.599 View mutations
280 P 19 0 19 0.100 0.731 View mutations
281 K 4 15 19 0.826 0.369 View mutations
282 Q 15 4 19 0.224 0.587 View mutations
283 R 3 16 19 0.759 0.359 View mutations
284 S 4 15 19 0.792 0.384 View mutations
285 K 1 18 19 0.891 0.427 View mutations
286 A 19 0 19 0.036 0.536 View mutations
287 R 16 3 19 0.248 0.472 View mutations
288 S 5 14 19 0.707 0.425 View mutations
289 C 18 1 19 0.058 0.542 View mutations
290 S 7 12 19 0.668 0.420 View mutations
291 E 3 16 19 0.729 0.446 View mutations
292 G 0 19 19 0.922 0.553 View mutations
293 R 15 4 19 0.230 0.457 View mutations
294 E 5 14 19 0.753 0.581 View mutations
295 C 7 12 19 0.628 0.528 View mutations
296 V 8 11 19 0.503 0.535 View mutations
297 N 0 19 19 0.996 0.660 View mutations
298 C 0 19 19 1.000 0.616 View mutations
299 G 0 19 19 1.000 0.706 View mutations
300 A 0 19 19 0.999 0.699 View mutations