P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 T 2 17 19 0.847 0.505 View mutations
177 P 0 19 19 0.997 0.633 View mutations
178 P 1 18 19 0.873 0.609 View mutations
179 K 1 18 19 0.903 0.471 View mutations
180 E 3 16 19 0.794 0.548 View mutations
181 V 17 2 19 0.132 0.457 View mutations
182 S 14 5 19 0.291 0.500 View mutations
183 P 1 18 19 0.869 0.514 View mutations
184 D 5 14 19 0.704 0.446 View mutations
185 P 19 0 19 0.028 0.561 View mutations
186 S 19 0 19 0.022 0.846 View mutations
187 T 19 0 19 0.004 0.831 View mutations
188 T 19 0 19 0.013 0.836 View mutations
189 G 13 6 19 0.347 0.574 View mutations
190 A 18 1 19 0.074 0.765 View mutations
191 A 19 0 19 0.022 0.781 View mutations
192 S 19 0 19 0.024 0.837 View mutations
193 P 10 9 19 0.482 0.493 View mutations
194 A 17 2 19 0.135 0.829 View mutations
195 S 18 1 19 0.115 0.920 View mutations
196 S 19 0 19 0.020 0.969 View mutations
197 S 19 0 19 0.004 0.960 View mutations
198 A 19 0 19 0.034 1.000 View mutations
199 G 19 0 19 0.025 0.990 View mutations
200 G 18 1 19 0.046 0.947 View mutations