P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 T 1 18 19 0.953 0.622 View mutations
302 A 10 9 19 0.469 0.493 View mutations
303 T 0 19 19 1.000 0.610 View mutations
304 P 0 19 19 0.975 0.633 View mutations
305 L 12 7 19 0.405 0.467 View mutations
306 W 1 18 19 0.964 0.526 View mutations
307 R 6 13 19 0.721 0.541 View mutations
308 R 9 10 19 0.513 0.506 View mutations
309 D 14 5 19 0.280 0.478 View mutations
310 G 14 5 19 0.293 0.498 View mutations
311 T 18 1 19 0.107 0.408 View mutations
312 G 19 0 19 0.002 0.289 View mutations
313 H 19 0 19 0.018 0.387 View mutations
314 Y 6 13 19 0.677 0.542 View mutations
315 L 1 18 19 0.952 0.658 View mutations
316 C 3 16 19 0.835 0.586 View mutations
317 N 1 18 19 0.946 0.632 View mutations
318 A 0 19 19 0.991 0.635 View mutations
319 C 0 19 19 1.000 0.611 View mutations
320 G 1 18 19 0.954 0.636 View mutations
321 L 0 19 19 0.999 0.713 View mutations
322 Y 2 17 19 0.913 0.600 View mutations
323 H 14 5 19 0.271 0.443 View mutations
324 K 0 19 19 1.000 0.629 View mutations
325 M 0 19 19 1.000 0.648 View mutations