P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 N 0 19 19 0.999 0.684 View mutations
327 G 3 16 19 0.851 0.623 View mutations
328 Q 0 19 19 0.982 0.584 View mutations
329 N 0 19 19 0.912 0.628 View mutations
330 R 1 18 19 0.957 0.599 View mutations
331 P 0 19 19 1.000 0.692 View mutations
332 L 0 19 19 1.000 0.670 View mutations
333 I 2 17 19 0.898 0.615 View mutations
334 K 0 19 19 1.000 0.592 View mutations
335 P 0 19 19 0.999 0.667 View mutations
336 K 5 14 19 0.739 0.545 View mutations
337 R 11 8 19 0.416 0.493 View mutations
338 R 1 18 19 0.945 0.557 View mutations
339 L 12 7 19 0.348 0.480 View mutations
340 S 6 13 19 0.739 0.542 View mutations
341 A 14 5 19 0.272 0.422 View mutations
342 A 4 15 19 0.802 0.610 View mutations
343 R 0 19 19 1.000 0.727 View mutations
344 R 0 19 19 0.993 0.719 View mutations
345 A 10 9 19 0.480 0.487 View mutations
346 G 0 19 19 1.000 0.756 View mutations
347 T 0 19 19 0.993 0.773 View mutations
348 C 6 13 19 0.631 0.558 View mutations
349 C 0 19 19 1.000 0.771 View mutations
350 A 1 18 19 0.926 0.789 View mutations