P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 N 0 19 19 1.000 0.838 View mutations
352 C 0 19 19 1.000 0.792 View mutations
353 Q 0 19 19 1.000 0.695 View mutations
354 T 0 19 19 1.000 0.808 View mutations
355 T 2 17 19 0.875 0.659 View mutations
356 T 4 15 19 0.752 0.622 View mutations
357 T 0 19 19 1.000 0.876 View mutations
358 T 0 19 19 1.000 0.821 View mutations
359 L 0 19 19 1.000 0.868 View mutations
360 W 1 18 19 0.946 0.762 View mutations
361 R 2 17 19 0.918 0.758 View mutations
362 R 0 19 19 1.000 0.879 View mutations
363 N 0 19 19 1.000 0.782 View mutations
364 A 1 18 19 0.947 0.740 View mutations
365 N 1 18 19 0.931 0.764 View mutations
366 G 0 19 19 1.000 0.864 View mutations
367 D 0 19 19 0.984 0.899 View mutations
368 P 0 19 19 1.000 0.917 View mutations
369 V 0 19 19 0.997 1.000 View mutations
370 C 1 18 19 0.934 0.802 View mutations
371 N 0 19 19 0.995 0.936 View mutations
372 A 10 9 19 0.479 0.478 View mutations
373 C 0 19 19 1.000 0.860 View mutations
374 G 0 19 19 1.000 0.855 View mutations
375 L 1 18 19 0.948 0.926 View mutations