P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 L 4 15 19 0.738 0.418 View mutations
127 H 0 19 19 0.917 0.332 View mutations
128 P 0 19 19 0.973 0.290 View mutations
129 S 15 4 19 0.271 0.636 View mutations
130 A 10 9 19 0.511 0.479 View mutations
131 A 7 12 19 0.600 0.396 View mutations
132 G 6 13 19 0.618 0.386 View mutations
133 G 15 4 19 0.254 0.662 View mutations
134 P 11 8 19 0.465 0.528 View mutations
135 G 18 1 19 0.064 0.836 View mutations
136 G 19 0 19 0.043 0.749 View mutations
137 P 14 5 19 0.248 0.640 View mutations
138 L 19 0 19 0.042 0.700 View mutations
139 S 19 0 19 0.066 0.688 View mutations
140 V 14 5 19 0.314 0.549 View mutations
141 Y 12 7 19 0.416 0.484 View mutations
142 P 19 0 19 0.007 0.628 View mutations
143 G 19 0 19 0.002 0.903 View mutations
144 A 19 0 19 0.000 0.915 View mutations
145 G 19 0 19 0.001 0.924 View mutations
146 G 19 0 19 0.000 0.929 View mutations
147 G 18 1 19 0.080 0.854 View mutations
148 S 19 0 19 0.000 0.873 View mutations
149 G 19 0 19 0.014 0.901 View mutations
150 G 19 0 19 0.000 0.893 View mutations