P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 G 19 0 19 0.005 0.911 View mutations
152 S 14 5 19 0.281 0.681 View mutations
153 G 18 1 19 0.063 0.856 View mutations
154 S 19 0 19 0.001 0.863 View mutations
155 S 18 1 19 0.099 0.795 View mutations
156 V 19 0 19 0.031 0.764 View mutations
157 A 19 0 19 0.012 0.795 View mutations
158 S 19 0 19 0.045 0.729 View mutations
159 L 10 9 19 0.397 0.482 View mutations
160 T 19 0 19 0.050 0.804 View mutations
161 P 14 5 19 0.263 0.615 View mutations
162 T 16 3 19 0.179 0.704 View mutations
163 A 18 1 19 0.071 0.740 View mutations
164 A 15 4 19 0.179 0.631 View mutations
165 H 19 0 19 0.049 0.626 View mutations
166 S 16 3 19 0.188 0.598 View mutations
167 G 19 0 19 0.004 0.655 View mutations
168 S 10 9 19 0.380 0.457 View mutations
169 H 17 2 19 0.090 0.508 View mutations
170 L 18 1 19 0.040 0.455 View mutations
171 F 5 14 19 0.660 0.415 View mutations
172 G 18 1 19 0.072 0.480 View mutations
173 F 19 0 19 0.050 0.382 View mutations
174 P 18 1 19 0.112 0.428 View mutations
175 P 1 18 19 0.909 0.578 View mutations