P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 T 0 19 19 0.999 0.859 View mutations
327 T 0 19 19 1.000 0.825 View mutations
328 L 0 19 19 1.000 0.845 View mutations
329 W 0 19 19 1.000 0.780 View mutations
330 R 0 19 19 0.930 0.857 View mutations
331 R 0 19 19 1.000 0.842 View mutations
332 N 0 19 19 1.000 0.794 View mutations
333 A 1 18 19 0.954 0.704 View mutations
334 N 0 19 19 1.000 0.762 View mutations
335 G 0 19 19 1.000 0.891 View mutations
336 D 0 19 19 0.995 0.874 View mutations
337 P 9 10 19 0.546 0.521 View mutations
338 V 3 16 19 0.840 0.842 View mutations
339 C 1 18 19 0.946 0.797 View mutations
340 N 0 19 19 1.000 0.932 View mutations
341 A 4 15 19 0.694 0.772 View mutations
342 C 0 19 19 1.000 0.902 View mutations
343 G 0 19 19 1.000 0.907 View mutations
344 L 0 19 19 1.000 0.944 View mutations
345 Y 1 18 19 0.947 0.760 View mutations
346 Y 1 18 19 0.947 0.705 View mutations
347 K 0 19 19 1.000 0.770 View mutations
348 L 0 19 19 1.000 0.841 View mutations
349 H 0 19 19 1.000 0.740 View mutations
350 N 0 19 19 0.962 0.653 View mutations