P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 K 19 0 19 0.001 0.464 View mutations
102 A 19 0 19 0.019 0.622 View mutations
103 L 10 9 19 0.455 0.473 View mutations
104 G 7 12 19 0.645 0.400 View mutations
105 S 6 13 19 0.694 0.380 View mutations
106 H 16 3 19 0.238 0.635 View mutations
107 H 19 0 19 0.008 0.682 View mutations
108 T 16 3 19 0.156 0.628 View mutations
109 A 19 0 19 0.018 0.659 View mutations
110 S 19 0 19 0.044 0.553 View mutations
111 P 12 7 19 0.378 0.429 View mutations
112 W 8 11 19 0.572 0.436 View mutations
113 N 19 0 19 0.013 0.501 View mutations
114 L 18 1 19 0.047 0.445 View mutations
115 S 10 9 19 0.489 0.444 View mutations
116 P 18 1 19 0.132 0.440 View mutations
117 F 4 15 19 0.748 0.415 View mutations
118 S 18 1 19 0.065 0.545 View mutations
119 K 3 16 19 0.703 0.414 View mutations
120 T 16 3 19 0.126 0.588 View mutations
121 S 10 9 19 0.469 0.475 View mutations
122 I 15 4 19 0.235 0.574 View mutations
123 H 4 15 19 0.821 0.332 View mutations
124 H 7 12 19 0.724 0.393 View mutations
125 G 6 13 19 0.596 0.371 View mutations