P31749 (AKT1)

Overview
Predicted structure (AF):
AF-P31749-F1-model_v4
Uniprot entry:
P31749
Gene:
AKT1
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
5131 out of 9119 mutations
Pathogenic based on D2Deep prediction:
3988 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9119 mutations across 480 unique positions. There are 5131 benign and 3988 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 T 19 0 19 0.001 0.479 View mutations
102 A 12 7 19 0.391 0.483 View mutations
103 I 2 17 19 0.887 0.648 View mutations
104 Q 8 11 19 0.580 0.435 View mutations
105 T 17 2 19 0.131 0.474 View mutations
106 V 18 1 19 0.091 0.380 View mutations
107 A 19 0 19 0.005 0.412 View mutations
108 D 19 0 19 0.005 0.424 View mutations
109 G 19 0 19 0.000 0.480 View mutations
110 L 19 0 19 0.000 0.377 View mutations
111 K 19 0 19 0.000 0.627 View mutations
112 K 19 0 19 0.000 0.770 View mutations
113 Q 19 0 19 0.001 0.748 View mutations
114 E 19 0 19 0.031 0.763 View mutations
115 E 19 0 19 0.002 0.711 View mutations
116 E 19 0 19 0.012 0.735 View mutations
117 E 18 1 19 0.117 0.779 View mutations
118 M 19 0 19 0.001 0.794 View mutations
119 D 19 0 19 0.002 0.817 View mutations
120 F 19 0 19 0.001 0.874 View mutations
121 R 18 1 19 0.061 0.841 View mutations
122 S 19 0 19 0.002 0.921 View mutations
123 G 19 0 19 0.005 0.848 View mutations
124 S 19 0 19 0.002 0.884 View mutations
125 P 19 0 19 0.030 0.896 View mutations