P31749 (AKT1)

Overview
Predicted structure (AF):
AF-P31749-F1-model_v4
Uniprot entry:
P31749
Gene:
AKT1
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
5131 out of 9119 mutations
Pathogenic based on D2Deep prediction:
3988 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 5131 benign and 3988 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 R 1 18 19 0.918 0.593 View mutations
77 C 10 9 19 0.441 0.498 View mutations
78 L 0 19 19 0.996 0.559 View mutations
79 Q 5 14 19 0.757 0.555 View mutations
80 W 0 19 19 0.985 0.581 View mutations
81 T 3 16 19 0.834 0.603 View mutations
82 T 3 16 19 0.827 0.585 View mutations
83 V 5 14 19 0.754 0.537 View mutations
84 I 12 7 19 0.408 0.473 View mutations
85 E 0 19 19 0.976 0.651 View mutations
86 R 5 14 19 0.734 0.535 View mutations
87 T 8 11 19 0.634 0.436 View mutations
88 F 7 12 19 0.615 0.525 View mutations
89 H 19 0 19 0.005 0.503 View mutations
90 V 19 0 19 0.000 0.442 View mutations
91 E 19 0 19 0.003 0.462 View mutations
92 T 19 0 19 0.000 0.537 View mutations
93 P 19 0 19 0.012 0.530 View mutations
94 E 19 0 19 0.006 0.517 View mutations
95 E 11 8 19 0.372 0.440 View mutations
96 R 0 19 19 0.962 0.488 View mutations
97 E 19 0 19 0.017 0.495 View mutations
98 E 16 3 19 0.264 0.517 View mutations
99 W 0 19 19 0.931 0.584 View mutations
100 T 6 13 19 0.680 0.427 View mutations