P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
376 E 19 0 19 0.001 0.458 View mutations
377 A 5 14 19 0.763 0.518 View mutations
378 K 1 18 19 0.950 0.463 View mutations
379 S 19 0 19 0.011 0.522 View mutations
380 L 1 18 19 0.956 0.541 View mutations
381 L 18 1 19 0.109 0.259 View mutations
382 A 11 8 19 0.437 0.415 View mutations
383 G 1 18 19 0.905 0.539 View mutations
384 L 19 0 19 0.001 0.357 View mutations
385 L 5 14 19 0.771 0.600 View mutations
386 K 18 1 19 0.097 0.472 View mutations
387 K 4 15 19 0.641 0.567 View mutations
388 D 19 0 19 0.000 0.499 View mutations
389 P 2 17 19 0.899 0.608 View mutations
390 K 19 0 19 0.001 0.461 View mutations
391 Q 16 3 19 0.141 0.453 View mutations
392 R 13 6 19 0.293 0.465 View mutations
393 L 1 18 19 0.845 0.576 View mutations
394 G 19 0 19 0.011 0.370 View mutations
395 G 19 0 19 0.000 0.480 View mutations
396 G 19 0 19 0.000 0.497 View mutations
397 P 19 0 19 0.025 0.479 View mutations
398 S 17 2 19 0.103 0.564 View mutations
399 D 19 0 19 0.000 0.496 View mutations
400 A 19 0 19 0.012 0.508 View mutations