P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 R 19 0 19 0.002 0.433 View mutations
102 A 16 3 19 0.185 0.451 View mutations
103 I 3 16 19 0.872 0.635 View mutations
104 Q 3 16 19 0.801 0.443 View mutations
105 M 16 3 19 0.176 0.448 View mutations
106 V 18 1 19 0.049 0.401 View mutations
107 A 19 0 19 0.003 0.436 View mutations
108 N 19 0 19 0.044 0.442 View mutations
109 S 19 0 19 0.000 0.446 View mutations
110 L 19 0 19 0.000 0.491 View mutations
111 K 19 0 19 0.000 0.649 View mutations
112 Q 19 0 19 0.000 0.732 View mutations
113 R 19 0 19 0.000 0.681 View mutations
114 A 19 0 19 0.001 0.722 View mutations
115 P 19 0 19 0.001 0.882 View mutations
116 G 19 0 19 0.002 0.915 View mutations
117 E 19 0 19 0.002 0.822 View mutations
118 D 19 0 19 0.000 0.810 View mutations
119 P 19 0 19 0.004 0.859 View mutations
120 M 19 0 19 0.000 0.855 View mutations
121 D 19 0 19 0.001 0.800 View mutations
122 Y 19 0 19 0.003 0.832 View mutations
123 K 19 0 19 0.006 0.829 View mutations
124 C 19 0 19 0.002 0.858 View mutations
125 G 19 0 19 0.007 0.817 View mutations