P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 E 19 0 19 0.002 0.446 View mutations
102 T 17 2 19 0.093 0.420 View mutations
103 L 19 0 19 0.086 0.422 View mutations
104 D 4 15 19 0.752 0.401 View mutations
105 E 4 15 19 0.831 0.420 View mutations
106 G 15 4 19 0.267 0.467 View mutations
107 M 19 0 19 0.011 0.607 View mutations
108 Q 14 5 19 0.296 0.533 View mutations
109 I 19 0 19 0.002 0.509 View mutations
110 P 19 0 19 0.000 0.531 View mutations
111 S 19 0 19 0.020 0.524 View mutations
112 T 19 0 19 0.006 0.468 View mutations
113 Q 19 0 19 0.000 0.581 View mutations
114 F 18 1 19 0.052 0.609 View mutations
115 D 19 0 19 0.043 0.618 View mutations
116 A 19 0 19 0.002 0.652 View mutations
117 A 17 2 19 0.113 0.573 View mutations
118 H 19 0 19 0.022 0.588 View mutations
119 P 19 0 19 0.006 0.530 View mutations
120 T 19 0 19 0.011 0.489 View mutations
121 N 7 12 19 0.607 0.434 View mutations
122 V 11 8 19 0.388 0.417 View mutations
123 Q 3 16 19 0.734 0.524 View mutations
124 R 4 15 19 0.803 0.515 View mutations
125 L 0 19 19 0.981 0.466 View mutations