P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
676 V 15 4 19 0.217 0.493 View mutations
677 E 18 1 19 0.056 0.364 View mutations
678 L 4 15 19 0.788 0.557 View mutations
679 T 19 0 19 0.000 0.471 View mutations
680 S 16 3 19 0.149 0.410 View mutations
681 S 18 1 19 0.047 0.376 View mutations
682 L 15 4 19 0.269 0.460 View mutations
683 F 19 0 19 0.114 0.395 View mutations
684 R 16 3 19 0.163 0.464 View mutations
685 T 12 7 19 0.400 0.456 View mutations
686 E 7 12 19 0.631 0.425 View mutations
687 P 11 8 19 0.474 0.495 View mutations
688 M 19 0 19 0.001 0.676 View mutations
689 A 19 0 19 0.003 0.710 View mutations
690 W 17 2 19 0.247 0.600 View mutations
691 N 19 0 19 0.000 0.789 View mutations
692 E 19 0 19 0.000 0.770 View mutations
693 T 19 0 19 0.000 0.807 View mutations
694 A 19 0 19 0.001 0.795 View mutations
695 D 19 0 19 0.001 0.808 View mutations
696 L 19 0 19 0.001 0.869 View mutations
697 G 19 0 19 0.000 0.877 View mutations
698 L 19 0 19 0.000 0.870 View mutations
699 D 19 0 19 0.001 0.853 View mutations
700 I 19 0 19 0.001 0.891 View mutations