P46109 (P46109)

Overview
Predicted structure (AF):
AF-P46109-F1-model_v4
Uniprot entry:
P46109
Gene:
P46109
Protein length:
303 residues
Mutations found:
5756
Benign based on D2Deep prediction:
2311 out of 5756 mutations
Pathogenic based on D2Deep prediction:
3445 out of 5756 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5756 mutations across 303 unique positions. There are 2311 benign and 3445 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 P 0 19 19 1.000 0.778 View mutations
177 Y 0 19 19 1.000 0.713 View mutations
178 V 0 19 19 0.983 0.738 View mutations
179 E 1 18 19 0.952 0.587 View mutations
180 K 3 16 19 0.843 0.427 View mutations
181 L 14 5 19 0.232 0.466 View mutations
182 V 19 0 19 0.005 0.567 View mutations
183 R 19 0 19 0.023 0.596 View mutations
184 S 19 0 19 0.014 0.669 View mutations
185 S 19 0 19 0.002 0.735 View mutations
186 P 19 0 19 0.000 0.777 View mutations
187 H 19 0 19 0.002 0.840 View mutations
188 G 19 0 19 0.000 0.857 View mutations
189 K 19 0 19 0.009 0.916 View mutations
190 H 19 0 19 0.003 0.887 View mutations
191 G 19 0 19 0.032 0.875 View mutations
192 N 19 0 19 0.010 0.922 View mutations
193 R 19 0 19 0.005 0.932 View mutations
194 N 19 0 19 0.041 0.924 View mutations
195 S 18 1 19 0.052 0.868 View mutations
196 N 19 0 19 0.007 0.920 View mutations
197 S 19 0 19 0.002 0.910 View mutations
198 Y 19 0 19 0.003 0.902 View mutations
199 G 19 0 19 0.014 0.900 View mutations
200 I 10 9 19 0.464 0.510 View mutations