P46109 (P46109)

Overview
Predicted structure (AF):
AF-P46109-F1-model_v4
Uniprot entry:
P46109
Gene:
P46109
Protein length:
303 residues
Mutations found:
5756
Benign based on D2Deep prediction:
2311 out of 5756 mutations
Pathogenic based on D2Deep prediction:
3445 out of 5756 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5756 mutations across 303 unique positions. There are 2311 benign and 3445 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 E 1 18 19 0.953 0.437 View mutations
127 Y 1 18 19 0.948 0.406 View mutations
128 V 0 19 19 1.000 0.560 View mutations
129 R 1 18 19 0.922 0.524 View mutations
130 T 0 19 19 1.000 0.608 View mutations
131 L 0 19 19 1.000 0.581 View mutations
132 Y 0 19 19 1.000 0.589 View mutations
133 D 0 19 19 1.000 0.613 View mutations
134 F 0 19 19 1.000 0.673 View mutations
135 P 12 7 19 0.292 0.484 View mutations
136 G 0 19 19 1.000 0.678 View mutations
137 N 1 18 19 0.943 0.596 View mutations
138 D 0 19 19 1.000 0.712 View mutations
139 A 7 12 19 0.628 0.523 View mutations
140 E 0 19 19 1.000 0.747 View mutations
141 D 0 19 19 1.000 0.822 View mutations
142 L 8 11 19 0.568 0.556 View mutations
143 P 19 0 19 0.007 0.296 View mutations
144 F 0 19 19 1.000 0.741 View mutations
145 K 18 1 19 0.093 0.418 View mutations
146 K 19 0 19 0.011 0.374 View mutations
147 G 5 14 19 0.702 0.625 View mutations
148 E 19 0 19 0.000 0.395 View mutations
149 I 13 6 19 0.365 0.399 View mutations
150 L 15 4 19 0.180 0.432 View mutations