P46109 (P46109)

Overview
Predicted structure (AF):
AF-P46109-F1-model_v4
Uniprot entry:
P46109
Gene:
P46109
Protein length:
303 residues
Mutations found:
5756
Benign based on D2Deep prediction:
2311 out of 5756 mutations
Pathogenic based on D2Deep prediction:
3445 out of 5756 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5756 mutations across 303 unique positions. There are 2311 benign and 3445 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 V 12 7 19 0.359 0.441 View mutations
152 I 0 19 19 0.988 0.570 View mutations
153 I 14 5 19 0.251 0.405 View mutations
154 E 5 14 19 0.695 0.548 View mutations
155 K 0 19 19 1.000 0.659 View mutations
156 P 0 19 19 0.988 0.627 View mutations
157 E 0 19 19 0.998 0.697 View mutations
158 E 1 18 19 0.947 0.685 View mutations
159 Q 0 19 19 0.994 0.662 View mutations
160 W 0 19 19 1.000 0.588 View mutations
161 W 0 19 19 1.000 0.578 View mutations
162 S 1 18 19 0.940 0.542 View mutations
163 A 0 19 19 1.000 0.647 View mutations
164 R 4 15 19 0.814 0.448 View mutations
165 N 17 2 19 0.115 0.397 View mutations
166 K 13 6 19 0.349 0.455 View mutations
167 D 11 8 19 0.384 0.418 View mutations
168 G 2 17 19 0.900 0.585 View mutations
169 R 18 1 19 0.076 0.443 View mutations
170 V 16 3 19 0.186 0.413 View mutations
171 G 0 19 19 1.000 0.696 View mutations
172 M 1 18 19 0.970 0.713 View mutations
173 I 0 19 19 0.980 0.802 View mutations
174 P 0 19 19 1.000 0.810 View mutations
175 V 0 19 19 0.997 0.770 View mutations