P48023 (FASLG)

Overview
Predicted structure (AF):
AF-P48023-F1-model_v4
Uniprot entry:
P48023
Gene:
FASLG
Protein length:
281 residues
Mutations found:
5338
Benign based on D2Deep prediction:
2681 out of 5338 mutations
Pathogenic based on D2Deep prediction:
2657 out of 5338 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5338 mutations across 281 unique positions. There are 2681 benign and 2657 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 S 15 4 19 0.276 0.551 View mutations
127 L 6 13 19 0.687 0.395 View mutations
128 E 4 15 19 0.777 0.386 View mutations
129 K 5 14 19 0.745 0.375 View mutations
130 Q 0 19 19 0.986 0.247 View mutations
131 I 1 18 19 0.926 0.260 View mutations
132 G 2 17 19 0.878 0.318 View mutations
133 H 17 2 19 0.152 0.724 View mutations
134 P 14 5 19 0.290 0.576 View mutations
135 S 18 1 19 0.071 0.756 View mutations
136 P 18 1 19 0.064 0.716 View mutations
137 P 17 2 19 0.095 0.592 View mutations
138 P 19 0 19 0.015 0.663 View mutations
139 E 19 0 19 0.113 0.566 View mutations
140 K 14 5 19 0.366 0.543 View mutations
141 K 18 1 19 0.045 0.659 View mutations
142 E 19 0 19 0.003 0.531 View mutations
143 L 19 0 19 0.000 0.510 View mutations
144 R 19 0 19 0.017 0.398 View mutations
145 K 19 0 19 0.099 0.468 View mutations
146 V 19 0 19 0.012 0.445 View mutations
147 A 16 3 19 0.233 0.376 View mutations
148 H 19 0 19 0.018 0.324 View mutations
149 L 15 4 19 0.260 0.404 View mutations
150 T 19 0 19 0.000 0.347 View mutations