P48023 (FASLG)

Overview
Predicted structure (AF):
AF-P48023-F1-model_v4
Uniprot entry:
P48023
Gene:
FASLG
Protein length:
281 residues
Mutations found:
5338
Benign based on D2Deep prediction:
2681 out of 5338 mutations
Pathogenic based on D2Deep prediction:
2657 out of 5338 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5338 mutations across 281 unique positions. There are 2681 benign and 2657 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 G 17 2 19 0.142 0.404 View mutations
152 K 4 15 19 0.766 0.501 View mutations
153 S 18 1 19 0.051 0.368 View mutations
154 N 17 2 19 0.104 0.494 View mutations
155 S 7 12 19 0.620 0.500 View mutations
156 R 13 6 19 0.304 0.421 View mutations
157 S 12 7 19 0.361 0.408 View mutations
158 M 13 6 19 0.312 0.411 View mutations
159 P 4 15 19 0.707 0.517 View mutations
160 L 1 18 19 0.920 0.644 View mutations
161 E 0 19 19 0.960 0.658 View mutations
162 W 0 19 19 1.000 0.717 View mutations
163 E 1 18 19 0.929 0.674 View mutations
164 D 1 18 19 0.937 0.702 View mutations
165 T 10 9 19 0.525 0.490 View mutations
166 Y 0 19 19 0.975 0.631 View mutations
167 G 1 18 19 0.916 0.668 View mutations
168 I 17 2 19 0.202 0.472 View mutations
169 V 17 2 19 0.114 0.416 View mutations
170 L 5 14 19 0.701 0.573 View mutations
171 L 10 9 19 0.445 0.495 View mutations
172 S 17 2 19 0.136 0.396 View mutations
173 G 17 2 19 0.177 0.389 View mutations
174 V 8 11 19 0.567 0.533 View mutations
175 K 15 4 19 0.255 0.467 View mutations