P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 P 0 19 19 0.984 0.795 View mutations
227 S 19 0 19 0.006 0.366 View mutations
228 S 4 15 19 0.735 0.583 View mutations
229 V 1 18 19 0.968 0.671 View mutations
230 C 0 19 19 1.000 0.673 View mutations
231 V 16 3 19 0.193 0.410 View mutations
232 G 1 18 19 0.971 0.607 View mutations
233 E 0 19 19 0.988 0.565 View mutations
234 E 6 13 19 0.690 0.444 View mutations
235 F 3 16 19 0.832 0.602 View mutations
236 Q 19 0 19 0.018 0.379 View mutations
237 I 3 16 19 0.838 0.578 View mutations
238 V 3 16 19 0.819 0.507 View mutations
239 L 2 17 19 0.896 0.586 View mutations
240 S 18 1 19 0.038 0.392 View mutations
241 G 1 18 19 0.909 0.660 View mutations
242 R 18 1 19 0.065 0.470 View mutations
243 G 13 6 19 0.415 0.476 View mutations
244 F 18 1 19 0.101 0.484 View mutations
245 M 17 2 19 0.082 0.452 View mutations
246 L 10 9 19 0.491 0.433 View mutations
247 G 19 0 19 0.001 0.496 View mutations
248 S 6 13 19 0.701 0.435 View mutations
249 R 18 1 19 0.157 0.582 View mutations
250 N 18 1 19 0.071 0.567 View mutations