P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 S 9 10 19 0.563 0.436 View mutations
277 M 18 1 19 0.058 0.452 View mutations
278 L 19 0 19 0.000 0.441 View mutations
279 C 3 16 19 0.859 0.587 View mutations
280 P 11 8 19 0.404 0.495 View mutations
281 A 0 19 19 0.999 0.594 View mutations
282 P 0 19 19 0.987 0.509 View mutations
283 I 18 1 19 0.065 0.431 View mutations
284 L 2 17 19 0.916 0.466 View mutations
285 N 15 4 19 0.223 0.519 View mutations
286 K 18 1 19 0.047 0.490 View mutations
287 A 19 0 19 0.029 0.456 View mutations
288 G 2 17 19 0.862 0.431 View mutations
289 E 16 3 19 0.174 0.489 View mutations
290 T 9 10 19 0.583 0.444 View mutations
291 L 10 9 19 0.577 0.434 View mutations
292 D 4 15 19 0.722 0.408 View mutations
293 V 19 0 19 0.000 0.489 View mutations
294 S 12 7 19 0.299 0.456 View mutations
295 V 19 0 19 0.000 0.491 View mutations
296 S 18 1 19 0.045 0.387 View mutations
297 F 8 11 19 0.620 0.503 View mutations
298 N 10 9 19 0.502 0.427 View mutations
299 G 11 8 19 0.467 0.456 View mutations
300 G 8 11 19 0.573 0.504 View mutations