P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 G 15 4 19 0.348 0.460 View mutations
252 S 18 1 19 0.089 0.511 View mutations
253 V 6 13 19 0.694 0.521 View mutations
254 L 19 0 19 0.001 0.423 View mutations
255 C 0 19 19 1.000 0.577 View mutations
256 T 14 5 19 0.302 0.448 View mutations
257 Y 4 15 19 0.766 0.449 View mutations
258 T 19 0 19 0.025 0.594 View mutations
259 V 18 1 19 0.125 0.486 View mutations
260 N 19 0 19 0.003 0.602 View mutations
261 E 17 2 19 0.127 0.577 View mutations
262 T 5 14 19 0.694 0.374 View mutations
263 Y 19 0 19 0.043 0.717 View mutations
264 T 16 3 19 0.254 0.576 View mutations
265 T 19 0 19 0.011 0.642 View mutations
266 S 18 1 19 0.119 0.627 View mutations
267 V 7 12 19 0.605 0.423 View mutations
268 K 18 1 19 0.070 0.515 View mutations
269 P 3 16 19 0.797 0.409 View mutations
270 V 15 4 19 0.289 0.539 View mutations
271 S 18 1 19 0.048 0.570 View mutations
272 V 19 0 19 0.007 0.382 View mutations
273 Q 18 1 19 0.075 0.534 View mutations
274 L 10 9 19 0.472 0.446 View mutations
275 N 17 2 19 0.113 0.431 View mutations