P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 K 19 0 19 0.006 0.453 View mutations
302 S 15 4 19 0.259 0.394 View mutations
303 V 14 5 19 0.300 0.424 View mutations
304 I 4 15 19 0.754 0.448 View mutations
305 S 19 0 19 0.031 0.449 View mutations
306 G 14 5 19 0.272 0.448 View mutations
307 S 19 0 19 0.015 0.500 View mutations
308 L 16 3 19 0.152 0.433 View mutations
309 I 19 0 19 0.078 0.579 View mutations
310 V 11 8 19 0.395 0.495 View mutations
311 T 18 1 19 0.072 0.487 View mutations
312 A 19 0 19 0.012 0.427 View mutations
313 T 19 0 19 0.001 0.503 View mutations
314 E 18 1 19 0.040 0.481 View mutations
315 C 9 10 19 0.546 0.431 View mutations
316 S 19 0 19 0.001 0.559 View mutations
317 N 19 0 19 0.001 0.637 View mutations
318 G 19 0 19 0.000 0.580 View mutations
319 I 19 0 19 0.033 0.660 View mutations
320 A 14 5 19 0.283 0.557 View mutations
321 A 11 8 19 0.406 0.486 View mutations
322 I 11 8 19 0.408 0.493 View mutations
323 I 14 5 19 0.294 0.547 View mutations
324 V 7 12 19 0.629 0.414 View mutations
325 I 6 13 19 0.665 0.400 View mutations