P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 L 11 8 19 0.438 0.462 View mutations
327 V 11 8 19 0.406 0.472 View mutations
328 L 4 15 19 0.779 0.390 View mutations
329 L 18 1 19 0.078 0.561 View mutations
330 L 14 5 19 0.263 0.490 View mutations
331 L 1 18 19 0.919 0.376 View mutations
332 L 6 13 19 0.662 0.409 View mutations
333 G 12 7 19 0.311 0.482 View mutations
334 I 4 15 19 0.789 0.410 View mutations
335 G 11 8 19 0.422 0.432 View mutations
336 L 12 7 19 0.348 0.414 View mutations
337 M 18 1 19 0.073 0.373 View mutations
338 W 6 13 19 0.708 0.542 View mutations
339 W 9 10 19 0.461 0.508 View mutations
340 F 0 19 19 0.976 0.687 View mutations
341 W 11 8 19 0.384 0.478 View mutations
342 P 0 19 19 0.998 0.831 View mutations
343 L 0 19 19 1.000 0.707 View mutations
344 C 0 19 19 1.000 0.643 View mutations
345 C 16 3 19 0.149 0.394 View mutations
346 K 10 9 19 0.424 0.495 View mutations
347 V 6 13 19 0.708 0.514 View mutations
348 V 7 12 19 0.603 0.501 View mutations
349 I 6 13 19 0.668 0.500 View mutations
350 K 19 0 19 0.044 0.529 View mutations