P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 D 15 4 19 0.255 0.481 View mutations
352 P 18 1 19 0.051 0.574 View mutations
353 P 6 13 19 0.658 0.389 View mutations
354 P 3 16 19 0.712 0.317 View mutations
355 P 15 4 19 0.205 0.622 View mutations
356 P 18 1 19 0.059 0.710 View mutations
357 A 19 0 19 0.018 0.774 View mutations
358 P 9 10 19 0.518 0.460 View mutations
359 A 16 3 19 0.203 0.683 View mutations
360 P 13 6 19 0.356 0.580 View mutations
361 K 17 2 19 0.100 0.711 View mutations
362 E 18 1 19 0.074 0.707 View mutations
363 E 6 13 19 0.708 0.381 View mutations
364 E 6 13 19 0.674 0.380 View mutations
365 E 19 0 19 0.049 0.594 View mutations
366 E 13 6 19 0.327 0.484 View mutations
367 P 18 1 19 0.034 0.503 View mutations
368 L 10 9 19 0.479 0.436 View mutations
369 P 18 1 19 0.057 0.382 View mutations
370 T 19 0 19 0.001 0.373 View mutations
371 K 14 5 19 0.263 0.485 View mutations
372 K 10 9 19 0.488 0.493 View mutations
373 W 0 19 19 1.000 0.679 View mutations
374 P 1 18 19 0.903 0.802 View mutations
375 T 10 9 19 0.463 0.483 View mutations