P61073 (CXCR4)

Overview
Predicted structure (AF):
AF-P61073-F1-model_v4
Uniprot entry:
P61073
Gene:
CXCR4
Protein length:
352 residues
Mutations found:
6687
Benign based on D2Deep prediction:
2592 out of 6687 mutations
Pathogenic based on D2Deep prediction:
4095 out of 6687 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6687 mutations across 352 unique positions. There are 2592 benign and 4095 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 I 0 19 19 1.000 0.878 View mutations
127 L 0 19 19 1.000 0.968 View mutations
128 A 0 19 19 1.000 0.967 View mutations
129 F 0 19 19 1.000 0.876 View mutations
130 I 0 19 19 1.000 0.963 View mutations
131 S 0 19 19 1.000 0.958 View mutations
132 L 0 19 19 1.000 0.809 View mutations
133 D 0 19 19 1.000 0.864 View mutations
134 R 0 19 19 0.999 0.914 View mutations
135 Y 0 19 19 1.000 0.823 View mutations
136 L 0 19 19 1.000 0.762 View mutations
137 A 0 19 19 1.000 0.847 View mutations
138 I 1 18 19 0.948 0.751 View mutations
139 V 0 19 19 1.000 0.730 View mutations
140 H 2 17 19 0.918 0.577 View mutations
141 A 0 19 19 1.000 0.708 View mutations
142 T 4 15 19 0.763 0.553 View mutations
143 N 15 4 19 0.216 0.493 View mutations
144 S 5 14 19 0.733 0.458 View mutations
145 Q 13 6 19 0.276 0.441 View mutations
146 R 19 0 19 0.001 0.486 View mutations
147 P 12 7 19 0.331 0.439 View mutations
148 R 19 0 19 0.006 0.461 View mutations
149 K 15 4 19 0.222 0.406 View mutations
150 L 19 0 19 0.000 0.364 View mutations