P61073 (CXCR4)

Overview
Predicted structure (AF):
AF-P61073-F1-model_v4
Uniprot entry:
P61073
Gene:
CXCR4
Protein length:
352 residues
Mutations found:
6687
Benign based on D2Deep prediction:
2592 out of 6687 mutations
Pathogenic based on D2Deep prediction:
4095 out of 6687 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 6687 mutations across 352 unique positions. There are 2592 benign and 4095 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 N 19 0 19 0.007 0.586 View mutations
177 V 18 1 19 0.059 0.524 View mutations
178 S 19 0 19 0.000 0.682 View mutations
179 E 19 0 19 0.001 0.682 View mutations
180 A 18 1 19 0.038 0.737 View mutations
181 D 19 0 19 0.001 0.728 View mutations
182 D 19 0 19 0.001 0.674 View mutations
183 R 19 0 19 0.002 0.656 View mutations
184 Y 18 1 19 0.056 0.615 View mutations
185 I 19 0 19 0.004 0.533 View mutations
186 C 18 1 19 0.104 0.365 View mutations
187 D 14 5 19 0.270 0.444 View mutations
188 R 17 2 19 0.143 0.497 View mutations
189 F 8 11 19 0.549 0.435 View mutations
190 Y 17 2 19 0.127 0.477 View mutations
191 P 1 18 19 0.911 0.468 View mutations
192 N 17 2 19 0.104 0.613 View mutations
193 D 16 3 19 0.196 0.591 View mutations
194 L 18 1 19 0.161 0.646 View mutations
195 W 15 4 19 0.302 0.401 View mutations
196 V 19 0 19 0.001 0.572 View mutations
197 V 19 0 19 0.024 0.541 View mutations
198 V 9 10 19 0.525 0.438 View mutations
199 F 19 0 19 0.022 0.479 View mutations
200 Q 6 13 19 0.690 0.439 View mutations