Q01130 (SRSF2)

Overview
Predicted structure (AF):
AF-Q01130-F1-model_v4
Uniprot entry:
Q01130
Gene:
SRSF2
Protein length:
221 residues
Mutations found:
4198
Benign based on D2Deep prediction:
2468 out of 4198 mutations
Pathogenic based on D2Deep prediction:
1730 out of 4198 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4198 mutations across 221 unique positions. There are 2468 benign and 1730 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 S 19 0 19 0.002 0.839 View mutations
102 R 19 0 19 0.011 0.870 View mutations
103 R 19 0 19 0.054 0.838 View mutations
104 G 7 12 19 0.608 0.385 View mutations
105 P 14 5 19 0.341 0.690 View mutations
106 P 18 1 19 0.068 0.851 View mutations
107 P 18 1 19 0.036 0.809 View mutations
108 R 19 0 19 0.009 0.904 View mutations
109 R 19 0 19 0.000 0.902 View mutations
110 Y 19 0 19 0.000 0.925 View mutations
111 G 19 0 19 0.000 0.935 View mutations
112 G 19 0 19 0.000 0.953 View mutations
113 G 19 0 19 0.000 1.000 View mutations
114 G 19 0 19 0.002 0.989 View mutations
115 Y 19 0 19 0.012 0.939 View mutations
116 G 19 0 19 0.001 0.904 View mutations
117 R 14 5 19 0.291 0.689 View mutations
118 R 19 0 19 0.002 0.871 View mutations
119 S 18 1 19 0.095 0.803 View mutations
120 R 19 0 19 0.023 0.871 View mutations
121 S 8 11 19 0.545 0.424 View mutations
122 P 16 3 19 0.172 0.740 View mutations
123 R 13 6 19 0.377 0.625 View mutations
124 R 18 1 19 0.150 0.855 View mutations
125 R 16 3 19 0.205 0.771 View mutations