O15143 (ARPC1B)

Overview
Predicted structure (AF):
AF-O15143-F1-model_v4
Uniprot entry:
O15143
Gene:
ARPC1B
Protein length:
372 residues
Mutations found:
7067
Benign based on D2Deep prediction:
4500 out of 7067 mutations
Pathogenic based on D2Deep prediction:
2567 out of 7067 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7067 mutations across 372 unique positions. There are 4500 benign and 2567 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 V 8 11 19 0.615 0.436 View mutations
227 C 19 0 19 0.000 0.584 View mutations
228 L 8 11 19 0.551 0.436 View mutations
229 A 7 12 19 0.690 0.423 View mutations
230 D 19 0 19 0.036 0.693 View mutations
231 A 19 0 19 0.000 0.562 View mutations
232 D 19 0 19 0.000 0.683 View mutations
233 K 12 7 19 0.400 0.546 View mutations
234 K 13 6 19 0.289 0.573 View mutations
235 M 19 0 19 0.008 0.771 View mutations
236 A 19 0 19 0.001 0.692 View mutations
237 V 18 1 19 0.138 0.669 View mutations
238 A 14 5 19 0.267 0.553 View mutations
239 T 19 0 19 0.041 0.660 View mutations
240 L 19 0 19 0.008 0.515 View mutations
241 A 19 0 19 0.000 0.638 View mutations
242 S 18 1 19 0.084 0.552 View mutations
243 E 18 1 19 0.062 0.613 View mutations
244 T 19 0 19 0.001 0.588 View mutations
245 L 5 14 19 0.640 0.449 View mutations
246 P 17 2 19 0.136 0.452 View mutations
247 L 19 0 19 0.000 0.489 View mutations
248 L 6 13 19 0.659 0.429 View mutations
249 A 9 10 19 0.519 0.444 View mutations
250 L 7 12 19 0.638 0.426 View mutations