O15143 (ARPC1B)

Overview
Predicted structure (AF):
AF-O15143-F1-model_v4
Uniprot entry:
O15143
Gene:
ARPC1B
Protein length:
372 residues
Mutations found:
7067
Benign based on D2Deep prediction:
4500 out of 7067 mutations
Pathogenic based on D2Deep prediction:
2567 out of 7067 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7067 mutations across 372 unique positions. There are 4500 benign and 2567 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 S 19 0 19 0.003 0.609 View mutations
202 C 19 0 19 0.000 0.404 View mutations
203 G 19 0 19 0.000 0.373 View mutations
204 W 19 0 19 0.017 0.429 View mutations
205 V 7 12 19 0.589 0.505 View mutations
206 H 3 16 19 0.734 0.561 View mutations
207 G 11 8 19 0.486 0.433 View mutations
208 V 11 8 19 0.396 0.489 View mutations
209 C 17 2 19 0.122 0.409 View mutations
210 F 17 2 19 0.120 0.369 View mutations
211 S 15 4 19 0.241 0.415 View mutations
212 A 10 9 19 0.495 0.457 View mutations
213 S 7 12 19 0.569 0.428 View mutations
214 G 0 19 19 0.993 0.602 View mutations
215 S 18 1 19 0.045 0.511 View mutations
216 R 17 2 19 0.092 0.566 View mutations
217 V 17 2 19 0.147 0.429 View mutations
218 A 10 9 19 0.474 0.435 View mutations
219 W 10 9 19 0.451 0.431 View mutations
220 V 19 0 19 0.001 0.357 View mutations
221 S 19 0 19 0.022 0.390 View mutations
222 H 14 5 19 0.284 0.446 View mutations
223 D 19 0 19 0.000 0.423 View mutations
224 S 11 8 19 0.461 0.485 View mutations
225 T 19 0 19 0.025 0.433 View mutations