O15143 (ARPC1B)

Overview
Predicted structure (AF):
AF-O15143-F1-model_v4
Uniprot entry:
O15143
Gene:
ARPC1B
Protein length:
372 residues
Mutations found:
7067
Benign based on D2Deep prediction:
4500 out of 7067 mutations
Pathogenic based on D2Deep prediction:
2567 out of 7067 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7067 mutations across 372 unique positions. There are 4500 benign and 2567 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 V 9 10 19 0.454 0.510 View mutations
177 E 4 15 19 0.759 0.567 View mutations
178 E 19 0 19 0.018 0.405 View mutations
179 R 15 4 19 0.209 0.429 View mutations
180 P 17 2 19 0.137 0.376 View mutations
181 A 19 0 19 0.002 0.444 View mutations
182 P 19 0 19 0.018 0.372 View mutations
183 T 17 2 19 0.163 0.483 View mutations
184 P 18 1 19 0.101 0.471 View mutations
185 W 19 0 19 0.005 0.365 View mutations
186 G 19 0 19 0.005 0.320 View mutations
187 S 13 6 19 0.319 0.476 View mutations
188 K 18 1 19 0.140 0.450 View mutations
189 M 10 9 19 0.515 0.493 View mutations
190 P 18 1 19 0.091 0.382 View mutations
191 F 3 16 19 0.789 0.585 View mutations
192 G 6 13 19 0.655 0.542 View mutations
193 E 18 1 19 0.122 0.428 View mutations
194 L 15 4 19 0.203 0.384 View mutations
195 M 19 0 19 0.022 0.380 View mutations
196 F 19 0 19 0.004 0.499 View mutations
197 E 19 0 19 0.014 0.433 View mutations
198 S 19 0 19 0.047 0.575 View mutations
199 S 19 0 19 0.001 0.563 View mutations
200 S 13 6 19 0.350 0.523 View mutations