O15143 (ARPC1B)

Overview
Predicted structure (AF):
AF-O15143-F1-model_v4
Uniprot entry:
O15143
Gene:
ARPC1B
Protein length:
372 residues
Mutations found:
7067
Benign based on D2Deep prediction:
4500 out of 7067 mutations
Pathogenic based on D2Deep prediction:
2567 out of 7067 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7067 mutations across 372 unique positions. There are 4500 benign and 2567 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 E 2 17 19 0.864 0.599 View mutations
127 Q 3 16 19 0.755 0.449 View mutations
128 E 1 18 19 0.948 0.592 View mutations
129 N 16 3 19 0.165 0.374 View mutations
130 D 0 19 19 0.975 0.664 View mutations
131 W 3 16 19 0.883 0.595 View mutations
132 W 0 19 19 1.000 0.728 View mutations
133 V 8 11 19 0.626 0.555 View mutations
134 C 3 16 19 0.832 0.735 View mutations
135 K 12 7 19 0.363 0.411 View mutations
136 H 1 18 19 0.939 0.883 View mutations
137 I 0 19 19 0.998 0.920 View mutations
138 K 2 17 19 0.917 0.770 View mutations
139 K 2 17 19 0.882 0.722 View mutations
140 P 3 16 19 0.853 0.640 View mutations
141 I 11 8 19 0.391 0.462 View mutations
142 R 19 0 19 0.001 0.346 View mutations
143 S 19 0 19 0.000 0.023 View mutations
144 T 14 5 19 0.232 0.366 View mutations
145 V 19 0 19 0.011 0.293 View mutations
146 L 19 0 19 0.002 0.318 View mutations
147 S 4 15 19 0.775 0.599 View mutations
148 L 19 0 19 0.000 0.160 View mutations
149 D 16 3 19 0.194 0.331 View mutations
150 W 18 1 19 0.065 0.171 View mutations