O15143 (ARPC1B)

Overview
Predicted structure (AF):
AF-O15143-F1-model_v4
Uniprot entry:
O15143
Gene:
ARPC1B
Protein length:
372 residues
Mutations found:
7067
Benign based on D2Deep prediction:
4500 out of 7067 mutations
Pathogenic based on D2Deep prediction:
2567 out of 7067 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7067 mutations across 372 unique positions. There are 4500 benign and 2567 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 H 4 15 19 0.744 0.743 View mutations
152 P 0 19 19 1.000 1.000 View mutations
153 N 5 14 19 0.705 0.633 View mutations
154 N 7 12 19 0.567 0.571 View mutations
155 V 5 14 19 0.734 0.606 View mutations
156 L 15 4 19 0.286 0.328 View mutations
157 L 11 8 19 0.422 0.454 View mutations
158 A 4 15 19 0.762 0.632 View mutations
159 A 7 12 19 0.564 0.546 View mutations
160 G 3 16 19 0.870 0.697 View mutations
161 S 2 17 19 0.902 0.632 View mutations
162 C 3 16 19 0.863 0.572 View mutations
163 D 1 18 19 0.961 0.559 View mutations
164 F 2 17 19 0.854 0.630 View mutations
165 K 18 1 19 0.076 0.496 View mutations
166 C 9 10 19 0.562 0.434 View mutations
167 R 19 0 19 0.033 0.291 View mutations
168 I 3 16 19 0.817 0.580 View mutations
169 F 19 0 19 0.010 0.249 View mutations
170 S 19 0 19 0.003 0.289 View mutations
171 A 4 15 19 0.795 0.641 View mutations
172 Y 18 1 19 0.113 0.301 View mutations
173 I 19 0 19 0.009 0.217 View mutations
174 K 19 0 19 0.015 0.410 View mutations
175 E 5 14 19 0.650 0.576 View mutations