O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 S 18 1 19 0.168 0.563 View mutations
227 G 19 0 19 0.012 0.532 View mutations
228 S 16 3 19 0.202 0.550 View mutations
229 G 0 19 19 0.975 0.378 View mutations
230 T 8 11 19 0.562 0.428 View mutations
231 G 18 1 19 0.131 0.555 View mutations
232 K 2 17 19 0.885 0.361 View mutations
233 G 2 17 19 0.887 0.344 View mutations
234 I 6 13 19 0.647 0.397 View mutations
235 S 19 0 19 0.014 0.535 View mutations
236 G 19 0 19 0.003 0.448 View mutations
237 Y 9 10 19 0.487 0.435 View mutations
238 L 0 19 19 0.994 0.446 View mutations
239 P 0 19 19 0.975 0.440 View mutations
240 T 17 2 19 0.122 0.401 View mutations
241 L 8 11 19 0.545 0.434 View mutations
242 N 12 7 19 0.373 0.469 View mutations
243 E 0 19 19 0.963 0.437 View mutations
244 D 17 2 19 0.081 0.500 View mutations
245 E 14 5 19 0.388 0.499 View mutations
246 E 17 2 19 0.155 0.540 View mutations
247 W 19 0 19 0.014 0.661 View mutations
248 K 18 1 19 0.051 0.694 View mutations
249 C 12 7 19 0.480 0.535 View mutations
250 D 18 1 19 0.080 0.696 View mutations